Despite Washington's emphasis on adjusting its focus on Africa, it seems that US-Africa cooperation may still be a test of whether the US return to Africa can actually yield results or become just more empty talk.

US Secretary of State Antony Blinken has begun a tour of four African countries this week. He is scheduled to visit Cape Verde, Cote d'Ivoire, Nigeria and Angola from January 21 to 26, the US Department of State said in a statement. During his visit, he will discuss US-African partnerships in trade, infrastructure, climate, food, health security and other issues.

Since Blinken's trip to Africa comes days after Chinese Foreign Minister Wang Yi's recent visit to the continent, the timing has led some Western media outlets to draw a connection between the Biden administration's attention to Africa and the US competition with China.

While Molly Phee, assistant secretary of state for African affairs, dismissed the idea that the US is trying to compete with China in Africa, saying it's the press "who frame this as a US-China soccer match," it is an undeniable fact that African issues often struggle to garner attention in Washington due to business factors. 

This is also the fundamental reason why the US has had only slight engagement with Africa over the years. It is not hard to see that one of the key drivers of the Biden administration's increased engagement with Africa is the need to address what the US calls "competition" outside of the continent, rather than Africa's own development needs.

While the US appears to be working to address Africa's concerns over development issues, given its history of "much talk, little action" toward cooperation in Africa, it is questionable how sincere the Biden administration is in supporting Africa and strengthening economic partnerships with African countries.

For years, US-Africa trade has remained at a very low level, with a volume that's not comparable to that of the US with any of its top 10 trading partners. In 2000, US-Africa trade was $37.6 billion, and after more than two decades, that figure only came to $72.5 billion in 2022. In comparison, in 2000, trade between China and Africa stood at $10.6 billion, while in 2022, the figure surged to $282 billion. Needless to say, the gap in enthusiasm between China and the US in economic and trade exchanges with Africa is apparent.

Even though the US reportedly struck hundreds of trade and investment deals worth $14.2 billion with African nations in 2023, the credibility and sustainability of these investment promises are questioned among African countries, and the political conditions attached to US investments have often been seen as annoying. 

Many African countries are dissatisfied with the US pressuring them to take sides in global affairs, such as the Russia-Ukraine conflict. 

Compared with US-Africa cooperation, the advantages of China-Africa cooperation have been fully highlighted. The history of China-Africa cooperation dates back to the 1960s. China has been the most consistent partner and supporter of the continent's development. 

In recent years, driven by the Forum on China-Africa Cooperation, the Belt and Road Initiative and other mechanisms, Chinese companies have made significant contributions to Africa's economic and social development, particularly in infrastructure and agriculture.

After China has invested heavily in Africa's infrastructure and economic development for decades, the US seems to have just realized the potential and importance of African countries. While US politicians have chosen to emphasize economic cooperation, their underlying geopolitical intentions in Africa are difficult to conceal.

In the meantime, with the rise of the "Global South," Africa's strategic focus and judgment have been strengthened. The US seeks to impress Africa, but a single visit alone cannot achieve that.

A delegation of senior Japanese business leaders, led by the head of the Japan-China Economic Association (JCEA) Shindo Kosei, has been visiting China since Tuesday, the first such visit in four years.

Observers and industry insiders said on Wednesday that they expect the ongoing visit could lead to more common ground in bilateral cooperation, such as facilitating people-to-people exchanges and green-energy activities, while bringing more positivity to China-Japan relations, which have hit a number of geopolitical setbacks in recent months.

The delegation, which is scheduled to stay through Friday, will discuss a wide range of economic issues with the Chinese side.

About 200 people are participating in the trip to China, including Masakazu Tokura, chairman of the Japan Business Federation and Ken Kobayashi, chairman of the Japan Chamber of Commerce and Industry, the Japan News reported on Wednesday.

"It marks the 46th time that a Japanese business delegation visited China since 1975…We hope that through exchange and dialogue with the Chinese side, the two countries could rebuild a trustworthy and friendly cooperation environment, and develop complementary, mutual learning and improving cooperation mechanisms," the JCEA said in a statement sent to the Global Times.

China and Japan are Asian neighbors and the second- and third-largest economies in the world. Under the current international situation, "it is of increasing necessity for the two countries to strengthen cooperation based on a spirit of mutual trust," the association added.

The delegation's composition is of substantial scale, which underscores the significant importance that the Japanese business community attaches to China-Japan economic relations, Xiang Haoyu, a research fellow at the China Institute of International Studies, told the Global Times on Wednesday.

The visit is widely seen as sending a positive signal for bilateral economic relations, and it also mirrors the desire of the Japanese business community to maintain dialogue with China and expand cooperation, especially at a time when Japan's economy is struggling with a lack of indigenous drive, and as bilateral trade and investment slowed or fell last year, observers said.

China is Japan's largest trading partner and one of the top investment destinations for Japanese companies. In 2023, China's exports to Japan dropped 8.4 percent year-on-year, while imports from Japan declined 12.9 percent, customs data showed.

It is not in the interests of the majority of the Japanese business community to impose trade curbs on shipments to China, Chen Zilei, director of the Research Center for Japanese Economics at the Shanghai University of International Business and Economics, told the Global Times on Wednesday.

China-Japan relations have been overshadowed by China-US relations. The Fumio Kishida government has for some time followed the US strategy of containing China, such as by restricting exports of advanced chipmaking equipment to China in 2023.

Ahead of the visit, Ren Hongbin, chairman of the China Council for the Promotion of International Trade, met with Japanese Ambassador to China Kenji Kanasugi in Beijing on Monday, during which they conducted in-depth communication on topics involving facilitating pragmatic cooperation between Chinese and Japanese businesses, as well as the World Expo 2025 in Osaka.

Chen expected that the Japanese side could discuss opening more direct flights and creating more convenience for business exchanges, as well as expanding areas of cooperation, as economic ties between the two countries remain complementary.

But Chen also stressed that other requests of the Japanese side should be made on the basis of "respecting the national security of China and the safety and health of Chinese citizens."

According to a report by the Nikkei, the delegation could also express the hope for the Chinese authorities to lift the ban on seafood imports from Japan, following the latter's dumping of nuclear-contaminated wastewater into the ocean.

It is also hoped that the deepening of bilateral economic ties would create a positive environment and conditions for easing and stabilization in China-Japan relations, observers said.

According to a survey recently released by the Global Times Institute, nearly 60 percent of respondents from 19 countries, including Japan, expressed the desire for their countries to have closer and friendlier relations with China.

China hopes that the EU could uphold fair and justice in addressing the China-EU economic and trade issues to further promote business relations, said Chinese Premier Li Qiang when meeting with European Commission President Ursula von der Leyen on Tuesday during the World Economic Forum Annual Meeting 2024, the Xinhua News Agency reported.

"It is hoped that the EU will uphold justice, compliance and transparency in economic and trade matters, treat Chinese enterprises fairly, and prudently introduce restrictive economic and trade policies and deploy trade remedies," Li said.

China stands ready to import more products from the EU that align with market demand, and hopes the EU will relax export restrictions on high-tech products to China, Li noted, adding that it is hoped that the two sides will work together in the same direction to push for more balanced development in bilateral trade.

China pledged to continue fostering a market-oriented, law-based and internationalized business climate, and willing to work with the EU to jointly abide by the basic norms governing market economy, he said.

Li called on the two sides to take the next meeting of the China-EU High-Level People-to-People Dialogue mechanism as an opportunity to strengthen dialogue and cooperation in education, science and technology, culture and tourism, and accelerate the resumption of personnel exchanges to inject new vitality into China-EU relations.

China is willing to work with the EU to implement important areas of consensus reached in the China-EU Summit, and make bilateral ties more stable, constructive, and reciprocal, so as to better promote the prosperity and development of China, the EU and the broader world, he added.

Von der Leyen said that the EU appreciates China's continuous opening-up and does not intend to "decouple" from China. She said that EU is ready to work with China in tackling climate change and promoting the reform of the World Trade Organization and further develop bilateral relationship.

China-US exchanges in various fields got off to a good start in 2024. On the first day of the New Year, leaders of the two countries exchanged congratulatory letters on the 45th anniversary of the establishment of diplomatic relations between the two countries. Then the 17th China-US Defense Policy Coordination Talks were held in Washington from January 8 to 9. On Tuesday, Liu Jianchao, head of the International Department of the Communist Party of China (CPC) Central Committee, visited the US and was invited to deliver a speech at the Council on Foreign Relations and engaged in communication with the US side. Meanwhile, the Peking University Table Tennis Team's visit to the US and the University of Virginia Table Tennis Team's visit to China replayed the classic scene in the history of China-US relations, where the small ball pushes the big ball.

The simultaneous exchanges at the military, diplomatic and civilian fields are remarkable in this period as China-US relations are stabilizing and rebounding. The resumption and closeness of exchanges is what the Chinese and US societies as well as the international community anticipate. If China-US relations are stable, the world situation will not be in chaos; if China-US relations are unstable, the rest of the world will become concerned.

The perceptions, policies and actions of the US toward China in recent years have once brought China-US relations to a low ebb and created huge risks and potential dangers for the world. The serious consequences of the US' short-sighted policies have forced it to engage in rational reflection, and the concerns and expectations of the international community have formed a synergy that has prompted the US to make certain adjustments in its relations with China. After the San Francisco meeting, the US has shown more enthusiasm than before in implementing the important consensus of the two heads of state, and we hope that this is the result of the US drawing the lessons from the twists and turns in China-US relations in the past year, and that it will not make the same mistakes again.

Signs of relaxation in China-US relations also emerged at the beginning of 2023, but were quickly disrupted by the US sensationalizing the "balloon incident." Many actual actions by the US on issues concerning Taiwan Straits, the South China Sea, and high-tech exports to China not only failed to implement the consensus reached by the leaders and the commitments of US President Joe Biden but some instead went in the completely opposite direction, creating one vortex after another in bilateral relations. This year, China-US relations need to break free from these whirlpools.

Regarding China-US relations, China has consistently emphasized mutual respect, peaceful coexistence, and win-win cooperation. The US should genuinely meet China halfway. As long as the US continues to categorize China as a "competitor" or even a "threat," all of its policies toward China will ultimately push China in that direction, and the US' gestures of easing tensions, as well as communication and exchanges, may be seen by China as mere tactical maneuvers or expedient measures without sincerity, or even with malicious intent. The US needs to work together with China to rebuild the basic political mutual trust; otherwise, it will be impossible to achieve a healthy, stable and sustained development of bilateral relations.

The US, on the one hand, is pushing for what it calls intense competition with China, while on the other hand, it is concerned that this competition might spiral out of control into conflict and confrontation. This in itself is contradictory. If the US seeks communication and exchanges solely for the purpose of competing with China "safely" without concerns, the effectiveness of such communication and exchanges will be limited. It is even less likely to guarantee that the competition initiated by the US will always stay within the "guardrails" envisioned by the US. The US should abandon this unrealistic idea as soon as possible.

In this round of communication, China has expressed its sincere desire for strengthened cooperation with the US and goodwill for peaceful coexistence. However, China has also reiterated its unwavering determination not to compromise or concede on the Taiwan question. The US must acknowledge and respect China's major concerns. On issues related to China's core interests, especially the Taiwan question, which is at the very core of China's core interests, the US must exercise caution and not cross red lines. This is a prerequisite for the correct handling of China-US relations. Without this foundation, meaningful discussions become impossible.

China has been a dependable partner in the development of the Maldives, and there are various areas in which both sides can strengthen bilateral cooperation under the China-proposed Belt and Road Initiative (BRI), ranging from the blue economy and digital economy to green technology, as well as infrastructure, the Maldives National Chamber of Commerce & Industry (MNCCI) told the Global Times.

The remarks came after the successful conclusion of the official visit to China of President of the Maldives Mohamed Muizzu from January 8 to 12. A slew of key cooperative projects were inked, as the two countries sought to deepen bilateral cooperation for win-win outcomes.

The presidential visit was eagerly anticipated by the business community in the Maldives, particularly with regard to fostering collaboration in enhancing tourism, facilitating secure infrastructure investments, and advancing cooperation in areas such as security, trade, and global challenges, the MNCCI said.

"China has consistently proven to be a dependable partner in the development of our nation," said the chamber.

China's participation in the economic development of the island nation has been evident under the BRI. One of the most prominent examples of recent Chinese investment is the China-Maldives Friendship Bridge, the first cross-sea bridge in the Maldives built by a Chinese company.

The bridge has significantly expanded economic connectivity, presenting numerous commercial prospects. According to the MNCCI, this has not only enhanced supply chain logistics but also led to the exploration of new housing opportunities, and development of the Youth City project in Hulhumale. The housing projects undertaken by Chinese investors have also propelled the development of the Youth City to unprecedented levels, the MNCCI said.

Another example is the expansion and upgrading of Ibrahim Nasir International Airport, with the participation of Chinese companies. This enhancement has significantly improved connectivity, bolstered tourism, and potentially created new employment opportunities.

Chinese investment, particularly in critical infrastructure projects, has injected much-needed capital for overall development, addressing essential areas such as housing, renewable energy, and waste management, the Maldives industry chamber said.

There are various areas where the chamber sees potential for enhanced cooperation with China, including the blue economy, which covers marine resources such as aquaculture and fisheries. Other areas are sustainable development and tourism.

The digital economy, in which China has expertise and technology is also an area that both sides can explore, including e-commerce, fintech and digital payments, the MNCCI said.
Green technology and infrastructure could also be areas for further cooperation with win-win outcomes, including climate resilient infrastructure, waste management and recycling.

The BRI has been a pivotal in the strengthened cooperation. Looking ahead, the Maldives business chamber said that "our future aspirations hinge on prioritizing sustainability initiatives... crucially, we emphasize the importance of training Maldivians to operate and maintain BRI projects, ensuring enduring benefits and contributing to the long-term success of these endeavors."

The MNCCI also underscored the need to preserve the strategic autonomy of the Maldives and diversification of partnerships to prevent an undue reliance on any single country.

Witnessed by 150 scientists from eight countries, the International PlateauPlus Association (PlateauPlus) was established Thursday in Beijing, during the PlateauPlus Workshop held by the Institute of Tibetan Plateau Research (ITP) and the Chinese Academy of Sciences (CAS).

PlateauPlus is a platform proposed by Chinese scientists that aims to unite top research institutions and scientists from more than 20 countries across the globe where giant plateaus are located. It is designated to serve as an international platform for mega plateau research and to develop a new model of interdisciplinary and cross-regional global cooperation in Earth system science, read a statement the ITPCAS sent to the Global Times.

The association will focus on the Qinghai-Tibet Plateau and Iranian Plateau in Asia, the Colorado Plateau and Columbia Plateau in North America, the Altiplano Plateau in South America, the East African Plateau in Africa and the Alps in Europe. It will conduct research on the formation and evolution of plateaus, environmental effects, biodiversity changes and human adaptation. It will also decipher the coupling mechanism between plateau uplift and surface environmental changes, and reveal the changes in plateau habitability and human social evolution, according to the ITPCAS.

Mega plateaus have significant impacts on the environment, biodiversity, and human survival. Previously, the ITPCAS mainly focused on studying the Qinghai-Tibet Plateau, which has also attracted many foreign scientists. However, besides the Qinghai-Tibet Plateau, other mega plateaus around the world also have a tremendous impact on these aspects. So it's a good idea to unite scientists all around the world to jointly examine all these mega plateaus and find out what factors have played a vital role or how these plateaus affect each other in shaping the current environmental landscape, rivers as well as human migration and adaptation, Ding Lin, an ITP researcher and Academician of the CAS and one of the initiators of PlateauPlus, told the Global Times.

"Although aspects of the orographic development of the Tibetan region are still actively debated, collaboration across disciplines and testing ideas within the rigor of mathematical models are honing our understanding of the highly complex natural processes inherent to the Tibetan geo/ecosystem. If humans are ever going to manage our planet in a responsible and informed way, then the lessons we have learned from Tibetan Plateau research must be applied more widely to other orographically complex systems. These lessons are not just those relating to the science itself, but how we do the research, how we improve our methodologies, how we nurture international collaboration and integrate local knowledge with broader global perspectives," said Robert Spicer, emeritus professor of Earth Sciences at The Open University in the UK.

"We now have a magnificent toolbox of methodologies and ideas that can be used to investigate other plateaus worldwide, so it is time to explore and integrate plateau system research globally," Spicer said. He noted that as a world leader in science, China is very attractive for foreign scientists.

During the two-day PlateauPlus Workshop, global scientists discussed the formation and evolution of plateaus, environmental effects, biodiversity changes, and human adaptation.

Ding said that in the future the ITPCAS will host workshops in different countries, fostering a truly global perspective.

Field excursions in various global mega plateaus will be a crucial part of the journey, offering hands-on experience and deeper insights. A key focus will be engaging more and more local institutions, especially from regions like East Africa and South America, which are currently underrepresented, according to Ding.

Strengthening these connections is essential for a more comprehensive understanding and inclusive approach to the research, he noted.

China recently verified a new morphing wing structure that can help build future cross-domain aircraft, with an expert saying on Tuesday that the cutting-edge technology is expected to undergo flight tests before being applied. 

The Aircraft Strength Research Institute of China, a subsidiary of the state-owned Aviation Industry Corporation of China (AVIC), successfully completed the theory verification on a full lattice distributed morphing wing structure based on mechanical metamaterials last week, AVIC said in an announcement posted on Sina Weibo on Monday.

During the verification, the morphing wing structure achieved distributed active torsional morph control, made breakthroughs in multiple core technologies including performance characterization of the mechanical metamaterials, cellular configuration design, reversible assembly of lattice structures, multi-point morph sensing and collaborative control, according to the announcement.

A video clip attached to the announcement shows a scaling model of a half-hollow lattice distributed wing structure changing its shape dynamically.

Wang Ya'nan, chief editor of Beijing-based Aerospace Knowledge magazine, told the Global Times on Tuesday that morphing wing is cutting-edge technology that enables aircraft to flexibly change form without using rigid rudder structures currently used on aircraft, which can only make limited moves in controlling the aircraft.

Morphing wing is like wings of birds that can make changes without many restrictions, enabling fine tunings, so it can provide better control over the aircraft, Wang said.

The technology can provide support to the design of future cross-domain variable geometry aircraft, AVIC said in the announcement.

A cross-domain aircraft is a type of aircraft designed to fly at very different altitudes, from low altitudes with dense atmosphere to high altitudes with thin air, as well as at very different velocities, from subsonic speeds to hypersonic speeds, Wang said. "This requires the aerodynamic shape of the aircraft to adjust based on the changes of the environment."

To achieve this goal, variable-sweep wing was developed, but it is still a rigid structure with limitations, Wang said, noting that the morphing wing can make flexible changes that can adapt to more flight environments, as long as the requirements of materials and structures are met.

Wang said he does not expect the new technology to be put into application any time soon, as he expects the morphing wing structure to undergo flight tests on demonstrators first, before being put on genuine aircraft for verification.

Chinese investment in Thailand is set to remain at a high level, reflecting a host of positive factors, after China became Thailand's largest foreign investor in 2023, Chinese and Thai analysts said on Wednesday.

Since December, at least 14 A-share listed companies have announced that they are setting up branches, building new plants, expanding existing facilities or increasing their capital in Thailand, amid an accelerated inflows of Chinese investment into Thailand, according to media reports.

ZYNP Corp, a combustion engine component maker from Central China's Henan Province, said in a stock filing on Wednesday that it is investing 210 million yuan ($29.56 million) to build a production base in Thailand.

Circuit Fabology Microelectronics Equipment Co, a printed circuit board (PCB) company based in East China's Anhui Province, announced on Wednesday that it is investing 100 million yuan in Thailand to set up a branch, buy land and build a plant.

Xu Genluo, vice president of Thailand-based Amata Corp, told the Global Times on Wednesday that the Chinese business community demonstrated an unprecedented passion to invest in Thailand last year and groups after groups of business delegations visited his industrial park.

Chinese and Thai analysts told the Global Times that rising Chinese investment is being driven by the new-energy vehicle (NEV) and electronics industries, with incentives by the Thai government. The world economic landscape, facing anti-globalization headwinds, has helped push this trend.

As the two sides work toward a China-Thailand Community with a Shared Future for Enhanced Stability, Prosperity and Sustainability, along with continued and accelerated growth in China-ASEAN trade and investment, Chinese companies' investment in Thailand will continue to surge, they predicted.

Lei Xiaohua, an ASEAN expert at the Guangxi Academy of Social Sciences in South China's Guangxi Zhuang Autonomous Region, told the Global Times on Wednesday that the Thai government has made economic development its top goal and regards attracting investment from China as one of the most important tools for economic development.

Chinese investors are also being attracted by Thailand's relatively complete supply chains and low-cost advantages, and the benefits and convenience brought by the Regional Comprehensive Economic Partnership trade pact that took effect on January 1, 2022, Lei said.

In a move that will boost people-to-people exchanges and commercial ties, Thai Prime Minister Srettha Thavisin announced on Tuesday that Thailand and China will permanently exempt each other's citizens from visa requirements, starting from March, China Media Group reported.

In response, Chinese Foreign Ministry spokesperson Wang Wenbin said that mutual visa exemptions serve the fundamental interests of both peoples, and the government departments responsible for the matter are in close communication on the specifics.

Boosted by the news, searches for the keyword "Bangkok" on Chinese travel platform Mafengwo surged by 200 percent as of Tuesday noon.

Huang Bin, head of the Chinese Department at the Bangkok-based Kasikorn Research Center, told the Global Times on Wednesday that almost all Chinese NEV brands invested in Thailand in 2023 due to incentives offered by the Thai government. Policies such as the EV3.5 program offer subsidies for the purchase of NEVs and aim to promote Thailand as the regional hub for these vehicles. For foreign investors, support policies include zero tariffs for imported used machine tools.

A reshaping of the global semiconductor supply chain also brought a large number of electronics firms, PCB companies in particular, to invest in Thailand, Huang said.

Huang predicted that the mutual visa exemption policy will boost bilateral trade and investment, though in a gradual fashion.

As China became Thailand's largest source of investment last year, the trend is expected to be maintained in 2024, the expert said.

China emerged as the largest source of foreign direct investment (FDI) applications, contributing 24 percent of FDI by value, with total investment pledges of 97.4 billion baht ($2.84 billion) for 264 projects in the first nine months of 2023, according to The Thailand Board of Investment.

In 2024, Thailand, Vietnam and Indonesia will be the highlight for Chinese overseas direct investment, Lei said.

As a cold wave swept across northern China, the Chinese capital welcomed its first snow of the winter on Sunday evening. Traffic in Beijing has also been affected by the snowfall, with heavy congestion during the morning rush hour on Monday.

Following the snowfall, Beijing was covered in a silver-white coat, presenting picturesque scenes at Beihai Park, the watchtowers and the Shenwu Gate of the Forbidden City. The snow covered the buildings of the Forbidden City, making the red walls and golden tiles appear more vibrant, creating a striking contrast with the pristine white snow, resulting in a beautiful and magnificent sight. Coincidentally, the Forbidden City is closed on Mondays, presenting a serene and peaceful atmosphere after the closure.

Different from the Forbidden City, the Universal Studios theme park is bustling as usual.  Many visitors wearing wizard robes headed straight to the Harry Potter's Wizarding World area, checking in at the silver-clad Hogsmeade Village, as if they have "traveled" into the classic snow scenes from the movies.

Netizens were amazed by the snowy scenes and expressed optimism for a prosperous year with auspicious snowfall. Many netizens from the southern regions expressed their envy, saying, "Beijing has already seen the first snow, while in Shenzhen, Guangdong Province, we still need to use electric fans. Southerners who have never seen snow are eager to personally experience it!"

Also enjoying the first snow was the star giant panda Meng Lan, "the 3rd Prince of Xizhimen," who once went viral for "breaking through" the enclosure at the Beijing Zoo. On the snowy day, Meng Lan rolled and happily frolicked in powedery snow. Visitors couldn't help but chuckle at the adorable sight.

From 7 pm on Sunday to 6 am on Monday, the average snowfall in Beijing was 5.1 millimeters, with the urban area averaging 5.8 millimeters. The highest snowfall occurred in Pupuwa, Fangshan district reaching 9.8 millimeters. According to Beijing Public Transport Group, as of 6 am, a total of 172 bus routes had been adjusted due to the snowy weather, including 157 routes that had been suspended, nine routes with adjusted sections, and six routes with detours and skipped stops.

The Beijing Capital International Airport plans to operate 1,100 flights and transport approximately 150,000 passengers on Monday. As of 7 am, 84 flights had been executed and 59 flights had been canceled. At 6 am, the airport initiated targeted de-icing operations, and a total of 22 flights had been de-iced. The overall operation of Beijing Capital International Airport remains normal.

Affected by a strong cold air mass, the meteorological department in East China's Shandong Province issued a blue warning for cold wave and a yellow warning for road icing on Saturday, and continued to issue a yellow warning for strong winds at sea on Sunday. Under the influence of the cold wave, there was also moderate to heavy snow and local blizzards in the northwest and central regions of Shandong. In addition, the city of Yulin in Northwest China's Shaanxi Province experienced significant rain and snow and a drop in temperatures on Sunday. Several local meteorological monitoring stations recorded snowfall at the level of heavy snow, and the average temperature dropped by 6 C to 8 C.

In Zhengzhou and Xinxiang, Central China's Henan Province, primary and secondary schools, as well as kindergartens, had half-day off on Monday.

On Sunday, a significant drop in temperatures occurred across most parts of Northeast China's Heilongjiang Province, with the lowest temperatures expected to reach -25 C to -30 C in some areas from December 10 to December 15. To cope with the cold weather, various measures had been taken to strengthen water and heating supply and other livelihood guarantees. In Fujin city, the local heating company has increased the frequency of inspections on heating equipment such as pipelines and valves to ensure the quality of heating.

To ensure the safety of passengers, the railway departments had suspended 112 passenger trains heading to Beijing, Xiamen, Chengdu, Taiyuan, among other routes, with some trains experiencing delays.

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have proposed a new "nano-micro composite" delivery concept for vaccines and developed a single-dose, dry-powder, inhalable vaccine platform. The vaccine made in the laboratory based on the technology is effective in blocking respiratory viral infection and transmission in animal test, showing great promise for combating future emerging and epidemic infectious diseases. This study was published in Nature on Wednesday. 

In recent years, researchers have made significant progress in developing vaccines for infectious respiratory diseases. However, most of these vaccines are administered through intramuscular injection, which primarily induces a humoral immune response and relies on blood antibodies to neutralize the virus. This approach fails to trigger a mucosal immune response and establish a robust immune barrier in the respiratory tract, according to a release from the research group.

The current liquid form of vaccines requires to be stored in strict low-temperature, and the two- or three-dose vaccination schedule also impacts the overall vaccination rate.

In confronting these problems, professor Wei Wei and professor Ma Guanghui from the State Key Laboratory of Biochemical Engineering at IPE, in cross-disciplinary collaboration with professor Wang Hengliang and professor Zhu Li from the State Key Laboratory of Pathogen and Biosecurity, have developed a new vaccine platform.

This platform combines biodegradable microspheres with protein nanoparticles. The surface of these nanoparticles can simultaneously display multiple antigens, thus inducing a broad-spectrum immune response and expanding the range of vaccine protection. The platform also allows for the quick and convenient development of other respiratory virus vaccines due to the flexibility of antigen presentation.

The platform's unique nano-micro composite structure enables an efficient immune response in the lungs by facilitating high-performance delivery. Once antigen-nanoparticles are released, they can be efficiently taken up by antigen-presenting cells. 

Moreover, this dry powder vaccine significantly reduces storage and transportation costs, making it suitable for areas with limited refrigeration facilities, thus improving immunization rates.

The sustained release of antigens in the vaccine induces long-lasting humoral, cellular, and mucosal immunity with just a single inhalation

In cooperation with professor He Zhanlong of the Institute of Medical Biology of the Chinese Academy of Medical Sciences, the researchers developed a model of airborne protection, close contact protection, and airborne transmission blocking, which demonstrated that an inhaled vaccine is highly effective in preventing the virus infection and transmission.

"The components of this nano-micro system used natural proteins and approved polymer materials, and the effectiveness and safety of the vaccine have been systematically studied in non-human primates, indicating its great potential for clinical translation," professor Wei said.